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KMID : 1007520140230010261
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Food Science and Biotechnology
2014 Volume.23 No. 1 p.261 ~ p.267
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Turmeric (Curcuma longa) Whole Powder Reduces Accumulation of Visceral Fat Mass and Increases Hepatic Oxidative Stress in Rats Fed a High-fat Diet
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Lee Chi-Ho
Kim Ah-Young
Pyun Chang-Won
Michihiro Fukushima
Han Kyu-Ho
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Abstract
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Turmeric powder (TP) containing approximately5.15% curcumin was evaluated for reduction of developmentof high-fat diet-induced obesity. Rats were fed a 30% fatdiet containing 5, 10, and 20 g of TP/100 g of diet (TP-5,TP-10, and TP-20 groups) for 30 days. Body weight gain,energy intake, and the visceral fat mass for the TP-10 andTP-20 groups were lower than for the control group.Serum triglyceride and hepatic total lipid levels for the TP-10 and TP-20 groups were lower than for the controlgroup. The hepatic glutathione concentration and theglutathione-S-transferase activity for all TP groups, and thethiobarbituric acid reactive substances level for the TP-20group, were higher than for the control group. A high doseof turmeric powder apparently reduces development ofhigh-fat diet-induced obesity, but also causes the adverseeffect of increasing oxidative stress in rats.
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KEYWORD
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curcumin, food intake, high-fat diet, obesity, turmeric
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